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InVivoMAb anti-rat Kappa Immunoglobulin Light Chain

Clone Catalog # Category
MAR 18.5 BE0122 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-rat Kappa Immunoglobulin Light Chain

The MAR 18.5 monoclonal antibody reacts with the kappa chain of the rat immunoglobulin light chain. The κ chain is one of two types of polypeptide subunits which make up the immunoglobulin light chain. A typical antibody is composed of two immunoglobulin heavy chains and two immunoglobulin light chains. The κ chain is coded for by V (variable), J (joining) and C (constant) genes. These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins. This antibody is used in combination with rat anti-mouse CD19 and CD22 (clones 1D3 and Cγ34.1) to deplete B cells in vivo.

InVivoMAb anti-rat Kappa Immunoglobulin Light Chain Specifications

Isotype

Mouse IgG2a, κ

Recomended Isotype Control(s) InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Soluble rat immunoglobulin

Reported Applications

in vivo B cell depletion in combination with anti-CD19 (clone 1D3) and anti-CD22 (clone Cy34.1)

Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark

RRID

AB_10951292