InVivoMAb anti-mouse CD22
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About InVivoMAb anti-mouse CD22
The Cy34.1 monoclonal antibody reacts with mouse CD22, a member of the SIGLEC family of lectins. CD22 is expressed at high levels on the surface of mature follicular and marginal zone B lymphocytes, B-1 cells, and plasma cells and associates with the B-cell antigen receptor. CD22 mediates B cell adhesion to ligands on endothelial cells in the bone marrow. Additionally, CD22 to negatively regulates B cell activation and prevents the development of autoimmune diseases. The Cy34.1 antibody has been shown to augment B cell proliferation in response to LPS or anti-mouse Ig µ chain.
InVivoMAb anti-mouse CD22 Specifications
Mouse IgG1, κ
|Recommended Isotype Control(s)||InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
B10.D2 mouse splenocytes
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.