InVivoMAb anti-mouse Notch4

Clone Catalog # Category
HMN4-14 BE0129 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse Notch4

The HMN4-14 monoclonal antibody reacts with mouse neurogenic locus notch homolog 4 (Notch4) a member of the Notch family of type 1 transmembrane proteins. The Notch signaling pathway is a highly conserved intercellular signaling pathway. Five Notch ligands have been identified including DLL4 and Jagged2. Upon ligand binding the Notch receptor undergoes proteolysis and translocates to the nucleus ultimately activating transcription. The Notch pathway has been shown to play a role in myeloid cell proliferation, hematopoiesis, and embryonic endothelial development.

InVivoMAb anti-mouse Notch4 Specifications

Isotype

Armenian Hamster IgG, κ

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Notch4-Fc recombinant protein

Reported Applications
  • in vitro Notch4 stimulation
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10948996