InVivoMAb anti-mouse MAdCAM-1
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About InVivoMAb anti-mouse MAdCAM-1
The MECA-367 monoclonal antibody reacts with mouse MAdCAM-1 (mucosal addressin cell adhesion molecule-1) a 50-60 kDa member of the Ig superfamily. MAdCAM-1 is primarily expressed on high endothelial venules in Peyer's patches, mesenteric lymph nodes and gut lamina propria. MAdCAM-1 interacts with LPAM-1 and CD62L to facilitate lymphocyte tethering, rolling, and homing. The MECA-367 antibody has been shown to block the interaction of MAdCAM-1 with its receptor in vivo and in vitro.
InVivoMAb anti-mouse MAdCAM-1 Specifications
Rat IgG2a, κ
|Recomended Isotype Control(s)||InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
Endothelial cells isolated from BALB/c mouse
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.