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InVivoMAb anti-mouse L-Selectin (CD62L)
Clone Catalog # Category
Mel-14 BE0021 InVivoMab Antibodies
$300 - 3080

The Mel-14 monoclonal antibody reacts with mouse CD62L also known as L-selectin and MEL-14. CD62L is a 76 kDa glycoprotein and a member of the selectin family that is expressed by neutrophils, monocytes, the majority of naïve T and B cells, a subset of memory T cells, NK cells, and most thymocytes. CD62L is a cell adhesion molecule that binds to many glycoprotein ligands including CD34, GlyCAM-1, MAdCAM-1, and PSGL-1 and acts as a "homing receptor" for lymphocytes to enter secondary lymphoid tissues via high endothelial venules.The Mel-14 monoclonal antibody reacts with mouse CD62L also known as L-selectin and MEL-14. CD62L is a 76 kDa glycoprotein and a member of the selectin family that is expressed by neutrophils, monocytes, the majority of naïve T and B cells, a subset of memory T cells, NK cells, and most thymocytes. CD62L is a cell adhesion molecule that binds to many glycoprotein ligands including CD34, GlyCAM-1, MAdCAM-1, and PSGL-1 and acts as a "homing receptor" for lymphocytes to enter secondary lymphoid tissues via high endothelial venules.

Isotype

Rat IgG2a

Recomended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

C3H/eb mouse B lymphoma 38C-13

Reported Applications

in vivo CD62L neutralization

Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark