InVivoMAb anti-mouse OX40L (CD134L)

Clone Catalog # Category
RM134L BE0033-1 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse OX40L (CD134L)

The RM134L monoclonal antibody reacts with mouse OX-40L also known as CD134L. OX-40L is a 35 kDa member of the TNF superfamily that is expressed on activated B cells and antigen presenting cells. OX40L is the ligand for OX-40 (CD134). OX-40 signaling regulates both CD4 and CD8 T cell clonal expansion. It provides a costimulatory signal to an antigen-reacting naive T cells to prolong proliferation, as well as augment the production of several cytokines including IL-2. In vivo treatment with the RM134L antibody has been shown to inhibit the poly(I:C)/CD40 stimulated proliferation of CD4 T cells.

InVivoMAb anti-mouse OX40L (CD134L) Specifications

Isotype

Rat IgG2b, κ

Recommended Isotype Control(s) InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Rat NRK-52E cells transfected with mouse OX40L

Reported Applications
  • in vivo blocking of OX40/OX40L signaling
  • in vitro OX40L neutralization
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assy
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_1107594

References provided by Bioz:

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