InVivoMAb anti-mouse CD276 (B7-H3)

Clone Catalog # Category
MJ18 BE0124 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse CD276 (B7-H3)

The MJ18 monoclonal antibody reacts with mouse CD276 also known as B7-H3. CD276 is a type I transmembrane protein and a member of the B7 family of co-stimulatory proteins. CD276 is expressed weakly on activated lymphocytes, macrophages, dendritic cells, nasal and airway epithelial cells, osteoblasts, and some tumor cell lines. A soluble form of CD276 is also secreted by monocytes, dendritic cells, and activated T cells. The biological role of CD276 is still under investigation however, recent studies suggest a negative regulatory role for CD276 in T cell responses. The MJ18 antibody has been shown to block CD276 when administered in vivo.

InVivoMAb anti-mouse CD276 (B7-H3) Specifications

Isotype

Rat IgG1, κ

Recommended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol(BE0290)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Mouse B7-H3 IgG2a fusion protein

Reported Applications
  • in vivo B7-H3 blockade
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10950149