InVivoMAb anti-mouse CD3ε

Clone Catalog # Category
KT3 BE0261 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse CD3ε

The KT3 monoclonal antibody reacts with mouse CD3ε, a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. CD3ε is one of five polypeptide chains that combine to form the TCR complex. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays roles in TCR signaling, T lymphocyte activation, and antigen recognition. The KT3 antibody has been shown to induce T lymphocyte activation via binding and stimulating the TCR.

InVivoMAb anti-mouse CD3ε Specifications

Isotype

Rat IgG2a

Recommended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

CBAT6 mouse thymocytes

Reported Applications
  • in vitro T cell negative selection
  • in vitro T cell stimulation/activation
  • Immunofluorescence
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_2687740