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InVivoMAb anti-mouse CSF1
Clone Catalog # Category
5A1 BE0204 InVivoMab Antibodies
$300 - 3080

The 5A1 monoclonal antibody reacts with mouse colony stimulating factor 1 (CSF1) also known as macrophage colony-stimulating factor (M-CSF). CSF1 is a hematopoietic growth factor that is expressed by many different cell types including fibroblasts, stromal cells, osteoblasts, activated T cells, macrophages, and B cells. CSF1 plays a role in regulating the proliferation, differentiation and survival of monocytes, macrophages, and bone marrow progenitor cells. CSF1 produced in vessel walls is thought to contribute to the development and progression of atherosclerosis. The 5A1 antibody has been shown to neutralize CSF1 in vivo.

Isotype

Rat IgG1

Recomended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 8.0 Dilution Buffer
Immunogen

Purified mouse CSF-1

Reported Applications

in vitro CSF1 neutralization

Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 8.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark