CONTRACT SERVICES

Bio X Cell offers custom fermentation and purification services for the production of monoclonal antibodies in cell culture. Bio X Cell employs state of the art fermentation technologies; including stirred tank fermenters and wavebag systems; our production capacity ranges from 5 to 500L.

Contract Production Of Antibodies

Bio X Cell provides production and purification services of antibodies produced from pre-existing hybridoma cell lines. These hybridomas are typically developed in the client’s laboratory or available in the public domain.

This service includes fermentation of the hybridoma in cell culture, harvest of the cell culture supernatant by centrifugation and concentration by 30 kDa ultrafiltration. Purification is performed by Protein A or G affinity chromatography. The purified antibody is dialyzed into PBS and filter sterilized. All of our custom products will be delivered with an endotoxin level < 2EU/mg. We also offer freezing of the cell line, on-site cell line storage and MAP testing for an additional fee.

All hybridomas submitted for contract production will first be evaluated in a small-scale pilot to determine whether the productivity is suitable to proceed to full scale. The fee for the pilot is $800 but will be waived if the production proceeds to full scale.

Pricing for 50 and 100 mg quantities is specified below. For information on contract production of quantities greater than 100 mg email customerservice@bxcell.com.

To begin, fill out and submit a Cell Line Information Form by clicking the button below. You will then receive a formal quote, and instructions for shipping cells.

PRICING

SIZE 50mg 100mg 200mg
ACADEMIC $1850 $2800 $4700
COMMERCIAL $2600 $4300 $7000
Fill out a Cell Line Information Form and Receive a Quote

Cell Line Information Form

  • **50mg Minimum**
  • **We will determine productivity within our system before moving to full scale, minimum is 20-30 mg/L**
  • If the isotype is unknown, Bio X Cell will determine the isotype for a $100 charge. It is necessary that we know the isotype in order to properly purify the antibody. Please check here to acknowledge this charge:
    • Assay S0034: Ultrasensitive qualitative detection of mouse hepatitis virus (MHV) by reverse transcription coupled real time PCR
    • Assay S0098: Ultrasensitive qualitative detection but not differentiation of mouse minute virus (MMV) and mouse parvovirus (MPV) by real time PCR
    • Assay S0099: Ultrasensitive qualitative detection of Sendai Virus (SEND) by reverse transcription coupled real time PCR
    • Assay S0102: Ultrasensitive qualitative detection of Theiler's murine encephalomyelitis virus by reverse transcription coupled real time PCR
    • Assay S0139: Ultrasensitive qualitative detection of pneumonia virus of mice by reverse transcription coupled real time PCR
    • Assay B0009: Ultrasensitive Mycoplasma screen by real time PCR. This screen detects but does not differentiate M. arginini, M. fermentans, M. hominis, M. hyorhinis, M. orale, M. pirum, M. salivarium, M. agassizii, M. cynos and others. This screen does not detect M. pneumoniae or M. pulmonis.
    • Panel P0029: Mouse Essentials Panel - Ultrasensitive detection and differentiation of the following pathogens using real time PCR protocols: MNV, MPV 1/2/3/4/5, MMV/MVM, MHV, REO-1, REO-2, REO-3, LCMV, LDV, MRV/EDIM, TMEV, ECTRO, HANTA, POLY, MAD1/MAV1, MAD2/MAV2, SEND, Mycoplasma pulmonis, PVM, mouse CMV, and K virus.

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Protecting your private information is our priority. This Statement of Privacy applies to https://bxcell.com/ and Bio X Cell and governs data collection and usage. For the purposes of this Privacy Policy, unless otherwise noted, all references to Bio X Cell include https://bxcell.com/. The Bio X Cell website is a ecommerce site. By using the Bio X Cell website, you consent to the data practices described in this statement.

Collection of your Personal Information

In order to better provide you with products and services offered on our Site, Bio X Cell may collect personally identifiable information, such as your:

If you purchase Bio X Cell's products and services, we collect billing and credit card information. Credit card information is not stored and is only used to complete the purchase transaction.

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Bio X Cell may also use your personally identifiable information to inform you of other products or services available from Bio X Cell and its affiliates.

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Bio X Cell may share data with trusted partners to help perform statistical analysis, send you email or postal mail, provide customer support, or arrange for deliveries. All such third parties are prohibited from using your personal information except to provide these services to Bio X Cell, and they are required to maintain the confidentiality of your information.

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Bio X Cell may keep track of the websites and pages our users visit within Bio X Cell, in order to determine what Bio X Cell services are the most popular. This data is used to deliver customized content and advertising within Bio X Cell to customers whose behavior indicates that they are interested in a particular subject area.

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Security of your Personal Information

Bio X Cell secures your personal information from unauthorized access, use, or disclosure. Bio X Cell uses the following methods for this purpose:

When personal information (such as a credit card number) is transmitted to other websites, it is protected through the use of encryption, such as the Secure Sockets Layer (SSL) protocol.

We strive to take appropriate security measures to protect against unauthorized access to or alteration of your personal information. Unfortunately, no data transmission over the Internet or any wireless network can be guaranteed to be 100% secure. As a result, while we strive to protect your personal information, you acknowledge that: (a) there are security and privacy limitations inherent to the Internet which are beyond our control; and (b) security, integrity, and privacy of any and all information and data exchanged between you and us through this Site cannot be guaranteed.

Children Under Thirteen

Bio X Cell does not knowingly collect personally identifiable information from children under the age of thirteen. If you are under the age of thirteen, you must ask your parent or guardian for permission to use this website.

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From time to time, Bio X Cell may contact you via email for the purpose of providing announcements, promotional offers, alerts, confirmations, surveys, and/or other general communication. In order to improve our Services, we may receive a notification when you open an email from Bio X Cell or click on a link therein.

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Changes to this Statement

Bio X Cell reserves the right to change this Privacy Policy from time to time. We will notify you about significant changes in the way we treat personal information by sending a notice to the primary email address specified in your account, by placing a prominent notice on our site, and/or by updating any privacy information on this page. Your continued use of the Site and/or Services available through this Site after such modifications will constitute your: (a) acknowledgment of the modified Privacy Policy; and (b) agreement to abide and be bound by that Policy.

Contact Information

Bio X Cell welcomes your questions or comments regarding this Statement of Privacy. If you believe that Bio X Cell has not adhered to this Statement, please contact Bio X Cell at:

Bio X Cell
10 Technology Drive, suite 2B West Lebanon, New Hampshire 03784

Email Address:
customerservice@bxcell.com

Telephone number:
1-866-787-3444

Effective as of February 01, 2019