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Product Application - Agonistic Antibodies

The use of agonistic monoclonal antibodies has emerged as one of the most effective ways to boost immune responses against infectious agents or to activate the immune response against tumor cells. Bio X Cell offers many agonistic monoclonal antibodies to immune checkpoint proteins including CD40, CD28, 4-1BB, OX-40, GITR, and BTLA. Additionally, we offer many anti-CD3 antibodies commonly used for stimulating T cell activation, differentiation and proliferation/expansion. These antibodies are highly pure with extremely low endotoxin levels and no preservatives or stabilizers making them ideal for in vivo injection and in vitro T cell stimulation. For information about the dosage and kinetics of administration for in vivo injection of these antibodies, we have compiled an up-to-date list of references for each antibody. These can be found on the individual product pages. We encourage you to review these papers and others in the literature to find the optimal protocol for your experimental system and goals.

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