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InVivoMAb anti-human YB-1
Clone Catalog # Category
21A3 BE0216 InVivoMab Antibodies
$300 - 3080

The 21A3 monoclonal antibody reacts with human Y-box binding protein 1 (YB-1) a highly conserved protein that has broad nucleic acid binding properties. YB-1 binds DNA and RNA and plays a role in multiple cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. YB-1 is also a component of messenger ribonucleoprotein complexes and may have a role in microRNA processing. Aberrant expression of YB-1 is associated with cancer proliferation in numerous tissues.

Isotype

Mouse IgG1

Recomended Isotype Control(s) InVivoMAb mouse IgG1 isotype control, unknown specificity
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Recombinant human YB-1

Reported Applications
  • Immunohistochemistry (paraffin)
  • Western blot
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark