InVivoMAb anti-rat β-2-Microglobulin

CloneCatalog #Category
4C9 BE0143InVivoMAb Antibodies
$150 - $3920 Login for Academic & Non-profit Pricing

About InVivoMAb anti-rat β-2-Microglobulin

The 4C9 monoclonal antibody reacts with rat beta 2 microglobulin (β2M) a 12 kDa component of MHC class I molecules. β-2-microglobulin, a non-membrane-anchored glycoprotein, noncovalently associates with the polymorphic heavy chain of MHC class I molecules to form the HLA class I antigen complex. β-2-microglobulin is expressed on all leukocytes, platelets, endothelial cells and epithelial cells and plays an essential role in mediating proper folding and expression of MHC class I molecules. The importance of β-2-microglobulin is illustrated by β-2-microglobulin knockout mice which show a normal distribution of T lymphocytes, but have no mature CD4 or CD8 T cells and are therefore defective in CD4 and CD8 T cell-mediated cytotoxicity. The 4C9 antibody recognizes rat β-2-microglobulin alone or complexed with FcRn heavy chains.

InVivoMAb anti-rat β-2-Microglobulin Specifications

Isotype Mouse IgG1
Immunogen Soluble neonatal Fc receptor (FcRn)
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAGE
Sterility 0.2 μM filtered
Production Purified from tissue culture supernatant in an animal free facility
Purification Protein G
RRID AB_10951294
Molecular Weight 150 kDa
Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.