InVivoMAb anti-mouse Thy1.2 (CD90.2)
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About InVivoMAb anti-mouse Thy1.2 (CD90.2)
The 30H12 monoclonal antibody reacts with mouse Thy1.2 also known as CD90.2. Thy1.2 is expressed by thymocytes and mature T lymphocytes as well as hematopoietic stem cells, neurons, epithelial cells, and fibroblasts. Thy1.2 is expressed only by certain mouse strains including C57BL/6, BALB/c, CBA, C3H, C58/, SJL, DBA, and NZB/. Thy1.2 is a 25-35 kDa GPI-anchored membrane glycoprotein and a member of the immunoglobulin superfamily. The function of Thy1.2 has not been fully elucidated but is thought to play roles in cognition, axon growth, T lymphocyte function, and apoptosis. The 30H12 monoclonal antibody has been reported to induce Ca2+ flux in thymocytes. This antibody is particularly useful for depletion of T lymphocytes.
InVivoMAb anti-mouse Thy1.2 (CD90.2) Specifications
Rat IgG2b, κ
|Recommended Isotype Control(s)||InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
Mouse thymus or spleen
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.