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InVivoMAb anti-mouse Thy1.2 (CD90.2)
Clone Catalog # Category
30H12 BE0066 InVivoMab Antibodies
$300 - 3080

The 30H12 monoclonal antibody reacts with mouse Thy1.2 also known as CD90.2. Thy1.2 is expressed by thymocytes and mature T lymphocytes as well as hematopoietic stem cells, neurons, epithelial cells, and fibroblasts. Thy1.2 is expressed only by certain mouse strains including C57BL/6, BALB/c, CBA, C3H, C58/, SJL, DBA, and NZB/. Thy1.2 is a 25-35 kDa GPI-anchored membrane glycoprotein and a member of the immunoglobulin superfamily. The function of Thy1.2 has not been fully elucidated but is thought to play roles in cognition, axon growth, T lymphocyte function, and apoptosis. The 30H12 monoclonal antibody has been reported to induce Ca2+ flux in thymocytes. This antibody is particularly useful for depletion of T lymphocytes.

Isotype

Rat IgG2b

Recomended Isotype Control(s) InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Mouse thymus or spleen

Reported Applications
  • in vivo ILC depletion
  • in vivo T cell depletion
  • Western blot
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark