InVivoMAb anti-mouse/human/rat CCL2 (MCP-1)

Clone Catalog # Category
2H5 BE0185 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse/human/rat CCL2 (MCP-1)

The 2H5 antibody reacts with mouse, human, and rat CCL2 also known as monocyte chemoattractant protein 1 (MCP-1). CCL2 is a 13 kDa chemokine that is produced mainly by monocytes/macrophages but is also expressed by endothelial, fibroblasts, epithelial, smooth muscle, mesangial, astrocytic, and microglial cells. It can be expressed constitutively or after induction by oxidative stress, cytokines, or growth factors. CCL2 regulates the migration and infiltration of monocytes, memory T lymphocytes, and NK cells and is implicated in the pathogeneses of several diseases characterized by monocytic infiltrates, such as multiple sclerosis, psoriasis, rheumatoid arthritis, and atherosclerosis. The 2H5 antibody has been shown to neutralize the biological effects of CCL2 in vivo.

InVivoMAb anti-mouse/human/rat CCL2 (MCP-1) Specifications


Armenian Hamster IgG, κ

Recommended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)

CHO-expressed mouse MCP-1

Reported Applications
  • in vivo CCL2 neutralization
  • Immunohistochemistry (frozen)
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAGE
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives

0.2 μM filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.



References provided by Bioz:

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