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InVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b
Clone Catalog # Category
4C2.4A7.5H11 BE0165 InVivoMab Antibodies
$300 - 3080

The 4C2.4A7.5H11 monoclonal antibody reacts with the mouse non-classical MHC class I molecule Qa-1b. Qa-1b is the functional homolog of HLA-E in humans and is characterized by its limited polymorphisms and small peptide repertoire. Qa-1b interacts with NK cells through the CD94/NKG2 family of receptors. Upon binding, Qa-1b signals NK cells not to engage in cell lysis.

Isotype

Mouse IgG1

Recomended Isotype Control(s) InVivoMAb mouse IgG1 isotype control, unknown specificity
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Peptide corresponding to residues 161-179 of Qa-1b

Reported Applications
  • Western blot
  • Immunofluorescence
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein A

Storage

Undiluted at 4°C in the dark