InVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b
The 4C2.4A7.5H11 monoclonal antibody reacts with the mouse non-classical MHC class I molecule Qa-1b. Qa-1b is the functional homolog of HLA-E in humans and is characterized by its limited polymorphisms and small peptide repertoire. Qa-1b interacts with NK cells through the CD94/NKG2 family of receptors. Upon binding, Qa-1b signals NK cells not to engage in cell lysis.
|Recomended Isotype Control(s)||InVivoMAb mouse IgG1 isotype control, unknown specificity|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer|
Peptide corresponding to residues 161-179 of Qa-1b
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
Undiluted at 4°C in the dark