InVivoMAb anti-mouse IL-9
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About InVivoMAb anti-mouse IL-9
The 9C1 monoclonal antibody reacts with mouse IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. IL-9 promotes mast cell and T cell proliferation, stimulates mast cell accumulation in tissues, promotes ILC survival, enhances class-switching to IgE in B cells and alters haematopoietic progenitor cell activity. Additionally, IL-9 enhances mucus production from airway epithelial cells and alters barrier function in the intestines. IL-9 is thought to contribute to asthma. The 9C1 antibody has been reported to block the bioactivity of IL-9.
InVivoMAb anti-mouse IL-9 Specifications
|Recomended Isotype Control(s)||InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
Mouse IL-9-OVA complex
in vivo IL-9 neutralization
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.