InVivoMAb anti-mouse/human IL-5

Clone Catalog # Category
TRFK5 BE0198 InVivoMab Antibodies
$95 - $3080
SDS Sheet

References provided by Bioz:


Powered by Bioz

About InVivoMAb anti-mouse/human IL-5

The TRFK5 monoclonal antibody reacts with mouse and human interleukin-5 (IL-5), a 26 kDa homodimeric cytokine. IL-5 stimulates B lymphocyte differentiation and proliferation and increases the secretion of IgM and IgA. It is also a key mediator in eosinophil activation and differentiation. IL-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. The TRFK5 antibody has been shown to neutralize the bioactivity of natural or recombinant IL-5.

InVivoMAb anti-mouse/human IL-5 Specifications

Isotype

Rat IgG1, κ

Recomended Isotype Control(s) InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol(BE0290)
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Mouse partially-purified T cell clone supernatant

Reported Applications
  • in vivo IL-5 neutralization
  • in vivo eosinophil depletion
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10950522