InVivoMAb anti-mouse Vγ2 TCR

Clone Catalog # Category
UC3-10A6 BE0168 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse Vγ2 TCR

The UC3-10A6 monoclonal antibody reacts with an epitope on the delta chain of the mouse Vγ2 TCR (V gamma 2 T cell receptor). Vγ2 TCR expressing T lymphocytes make up a large proportion of the γδ T cells in late fetal and adult thymus, peripheral lymphoid tissues, lung, intestinal epithelium, and epidermis. The exact function, ligand, and specificity of γδ TCR-expressing T cells are not completely understood. Studies suggest that these cells recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play a role in regulating the immune response during bacterial infection. The UC3-10A6 antibody has been shown to deplete γδ T cells when administered in vivo.

InVivoMAb anti-mouse Vγ2 TCR Specifications

Isotype

Armenian Hamster IgG, κ

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

G8 mouse T cells

Reported Applications
  • in vivo γδ T cell depletion
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10950109