InVivoMAb anti-mouse DR5 (CD262)

Clone Catalog # Category
MD5-1 BE0161 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse DR5 (CD262)

The MD5-1 monoclonal antibody reacts with mouse death receptor 5 (DR5) also known as CD262 and TRAIL-R2. DR5 is a 55 kDa member of the TNF receptor superfamily and is expressed by most cell types. Upon binding to its ligand TRAIL, DR5 activates NF-κB and induces TRAIL-mediated apoptosis. The MD5-1 antibody has been shown to induce TRAIL-mediated apoptosis in vitro and in vivo.

InVivoMAb anti-mouse DR5 (CD262) Specifications

Isotype

Armenian Hamster IgG, κ

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Mouse DR5-Ig fusion protein

Reported Applications
  • in vivo induction TRAIL-mediated apoptosis
  • in vitro induction TRAIL-mediated apoptosis
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10950391