InVivoMAb anti-mouse CD86 (B7-2)

Clone Catalog # Category
GL-1 BE0025 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse CD86 (B7-2)

The GL-1 monoclonal antibody reacts with mouse CD86 also known as B7-2. CD86 is an 80 kDa Ig superfamily member. CD86 is expressed by activated T and B cells, macrophages, and dendritic cells. This ligand binds to CD28 to provide a costimulatory signal necessary for T cell activation and survival, and cytokine production. Additionally, CD80 binds to CTLA-4 which inhibits T cells. This antibody has been shown to block CD86 in vivo and inhibit the priming of cytotoxic T cells.

InVivoMAb anti-mouse CD86 (B7-2) Specifications

Isotype

Rat IgG2a, κ

Recommended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

LPS-activated CBA/Ca mouse splenic B cells

Reported Applications
  • in vivo CD86 blockade
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_1107678

References provided by Bioz:

Disclaimer: These articles are provided by Bioz, an automated third-party article search engine. Given Bioz’s automation, these articles may not reflect the reported applications listed for this product. For an extensive up-to-date article list directly tailored to the reported applications listed for this product please see the Bio X Cell Application References by clicking the green button above.


Powered by Bioz

We're Heading to AACR

Come visit us at Booth 1842! See you in Atlanta!