InVivoMAb anti-mouse CD80 (B7-1)
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About InVivoMAb anti-mouse CD80 (B7-1)
The 16-10A1 monoclonal antibody reacts with mouse CD80 also known as B7-1. CD80 is a 60 kDa Ig superfamily member and is expressed by activated B cells and constitutively by monocytes and dendritic cells. This ligand binds to CD28 to provide a costimulatory signal necessary for T cell activation and survival, and cytokine production. Additionally, CD80 binds to CTLA-4 which inhibits T cells. This antibody has been shown to block CD80 in vivo.
InVivoMAb anti-mouse CD80 (B7-1) Specifications
Armenian Hamster IgG2
|Recommended Isotype Control(s)||InVivoMAb polyclonal Armenian hamster IgG(BE0091)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 8.0 Dilution Buffer(IP0080)|
CHO cell line transfected with mouse CD80
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.