InVivoMAb anti-mouse CD70

Clone Catalog # Category
FR70 BE0022 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse CD70

The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is expressed by activated mouse T and B lymphocytes and dendritic cells. CD70 is a ligand for CD27 and their interaction promotes T and B cell cross-stimulation and co-stimulation of B cell proliferation and immunoglobulin production. Cells expressing CD70 have been shown to co-stimulate T cell proliferation and induce cytokine production. The FR70 antibody is reported to block CD70 binding to CD27.

InVivoMAb anti-mouse CD70 Specifications

Isotype

Rat IgG2b, κ

Recommended Isotype Control(s) InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

BALB/c mouse B lymphoma A20.2J

Reported Applications
  • in vivo CD70 blockade
  • in vitro CD70 blockade
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_1107667