InVivoMAb anti-mouse CD70
The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is expressed by activated mouse T and B lymphocytes and dendritic cells. CD70 is a ligand for CD27 and their interaction promotes T and B cell cross-stimulation and co-stimulation of B cell proliferation and immunoglobulin production. Cells expressing CD70 have been shown to co-stimulate T cell proliferation and induce cytokine production. The FR70 antibody is reported to block CD70 binding to CD27.
|Recomended Isotype Control(s)||InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer|
BALB/c mouse B lymphoma A20.2J
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
Undiluted at 4°C in the dark