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InVivoMAb anti-mouse CD48
Clone Catalog # Category
HM48-1 BE0147 InVivoMab Antibodies
$300 - 3080

The HM48-1 monoclonal antibody reacts with mouse CD48 also known as BCM1, Blast-1 (human), and OX-45 (rat). CD48 is a 45 kDa GPI-anchored glycoprotein and a member of the SLAM family and Ig superfamily. CD48 is expressed on T and B lymphocytes as well as monocytes and macrophages. CD48 plays a critical role in adhesion and T cell activation. The primary ligands for CD48 are CD2 and CD244. The HM48-1 antibody is reported to block the CD48/CD2 and CD48/CD244 interactions in vivo as well as inhibit the proliferative response of mitogen-activated spleen cells, provide a co-stimulatory signal for activated T cells in vitro, and prolong cardiac allograft survival in vivo.

Isotype

Armenian Hamster IgG

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

MBL2 mouse T lymphoma cells

Reported Applications
  • in vivo CD48 blockade
  • in vitro CD48 blocking
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark