InVivoMAb anti-mouse CD48

Clone Catalog # Category
HM48-1 BE0147 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse CD48

The HM48-1 monoclonal antibody reacts with mouse CD48 also known as BCM1, Blast-1 (human), and OX-45 (rat). CD48 is a 45 kDa GPI-anchored glycoprotein and a member of the SLAM family and Ig superfamily. CD48 is expressed on T and B lymphocytes as well as monocytes and macrophages. CD48 plays a critical role in adhesion and T cell activation. The primary ligands for CD48 are CD2 and CD244. The HM48-1 antibody is reported to block the CD48/CD2 and CD48/CD244 interactions in vivo as well as inhibit the proliferative response of mitogen-activated spleen cells, provide a co-stimulatory signal for activated T cells in vitro, and prolong cardiac allograft survival in vivo.

InVivoMAb anti-mouse CD48 Specifications

Isotype

Armenian Hamster IgG

Recommended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

MBL2 mouse T lymphoma cells

Reported Applications
  • in vivo CD48 blockade
  • in vitro CD48 blocking
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_10949470

References provided by Bioz:

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