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InVivoMAb anti-mouse CD28
Clone Catalog # Category
37.51 BE0015-1 InVivoMab Antibodies
$350 - 3685

The 37.51 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. The 37.51 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.

Isotype

Syrian Hamster IgG2

Recomended Isotype Control(s) InVivoMAb polyclonal Syrian hamster IgG
Immunogen

C57BL/6 mouse T cell lymphoma EL-4 cells

Reported Applications
  • in vitro T cell stimulation/activation
  • in vivo CD28 blockade
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 6.0 0.01% Tween

  • Contains no stabilizers or preservatives

Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark