InVivoMAb anti-mouse CD28
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About InVivoMAb anti-mouse CD28
The PV-1 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. The PV-1 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells.
InVivoMAb anti-mouse CD28 Specifications
Armenian Hamster IgG, κ
|Recommended Isotype Control(s)||InVivoMAb polyclonal Armenian hamster IgG(BE0091)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
C57BL/6 mouse T cell lymphoma EL-4 cells
in vitro T cell stimulation/activation
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.