InVivoMAb anti-mouse CD209b (SIGN-R1)
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About InVivoMAb anti-mouse CD209b (SIGN-R1)
The 22D1 monoclonal antibody reacts with mouse CD209b also known as SIGN-R1. CD209b is a 37 kDa type II transmembrane C-type lectin receptor. CD209b is expressed on the surface of splenic marginal zone and lymph node medullary macrophages and is commonly used as a marker for these cells. The CD209b protein is involved in the innate immune response, it binds to and initiates uptake of various microorganisms by recognizing high-mannose-containing glycoproteins on their envelopes. The 22D1 antibody has been reported to block CD209b in vivo.
InVivoMAb anti-mouse CD209b (SIGN-R1) Specifications
Armenian Hamster IgG, κ
|Recommended Isotype Control(s)||InVivoMAb polyclonal Armenian hamster IgG(BE0091)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
C-terminal peptide of mouse SIGN-R1
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.