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InVivoMAb anti-mouse PSGL-1 (CD162)
Clone Catalog # Category
4RA10 BE0186 InVivoMab Antibodies
$300 - 3080

The 4RA10 monoclonal antibody reacts with mouse P-selectin glycoprotein ligand-1 (PSGL-1) also known as CD162. PSGL-1 is a 230 kDa glycoprotein that is expressed by bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and T lymphocytes. PSGL-1 is a ligand for P-selectin (CD62P) and plays roles in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. The 4RA10 antibody is reported to block the binding of mouse leukocytes to CD62P and CD62L.

Isotype

Rat IgG1

Recomended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Mouse PSGL-1 human IgG1 fusion protein

Reported Applications
  • in vivo PSGL-1 blockade
  • Immunohistochemistry (frozen)
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark