InVivoMAb anti-mouse IFNγR (CD119)
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About InVivoMAb anti-mouse IFNγR (CD119)
The GR-20 monoclonal antibody reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. CD119 heterodimerizes with IFNγ receptor 2 (AF-1) to form the IFNγR, a Class II cytokine receptor. The IFNγR is expressed ubiquitously on almost all cell types with the exception of mature erythrocytes. The GR-20 antibody binds to an epitope in the ligand-binding site of the receptor and has been shown to block the binding of IFNγ to CD119 therefore inhibiting IFNγ mediated effects.
InVivoMAb anti-mouse IFNγR (CD119) Specifications
Rat IgG2a, κ
|Recomended Isotype Control(s)||InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
BALB/c mouse monomyelocytic cell line WEHI-3
in vivo IFNγR neutralization
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.