• SHOP
  • QUOTE
InVivoMAb anti-mouse IFNγR (CD119)
Clone Catalog # Category
GR-20 BE0029 InVivoMab Antibodies
$300 - 3080

The GR-20 monoclonal antibody reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. CD119 heterodimerizes with IFNγ receptor 2 (AF-1) to form the IFNγR, a Class II cytokine receptor. The IFNγR is expressed ubiquitously on almost all cell types with the exception of mature erythrocytes. The GR-20 antibody binds to an epitope in the ligand-binding site of the receptor and has been shown to block the binding of IFNγ to CD119 therefore inhibiting IFNγ mediated effects.

Isotype

Rat IgG2a

Recomended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

BALB/c mouse monomyelocytic cell line WEHI-3

Reported Applications

in vivo IFNγR neutralization

Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark