InVivoMAb anti-mouse CD1d (CD1.1)
|20H2 (HB323)||BE0179||InVivoMab Antibodies|
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About InVivoMAb anti-mouse CD1d (CD1.1)
The 20H2 monoclonal antibody reacts with mouse CD1d also known as CD1.1. CD1d is a 48 kDa type I membrane glycoprotein and a member of the CD1 family of glycoproteins. CD1d is a non-classical MHC protein with structural homology to class I MHC molecules. CD1d is expressed on the surface of various antigen-presenting cells and is involved in the presentation of non-peptide glycolipid antigens to to CD1d-restricted T cells. CD1d-presented glycolipid antigens activate invariant natural killer T (iNKT) cells, through the interaction with the T-cell receptor present on iNKT cell membranes. When activated, iNKT cells rapidly produce Th1 and Th2 cytokines.
InVivoMAb anti-mouse CD1d (CD1.1) Specifications
Rat IgG1, κ
|Recommended Isotype Control(s)||
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol(BE0290)
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
CD1.1-transfected rat cell line RBL-CD1.1 followed by CD1.1-transfected human cell line CR1-CD1.1
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.