InVivoMAb anti-mouse PD-L2 (B7-DC)

Clone Catalog # Category
TY25 BE0112 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse PD-L2 (B7-DC)

The TY25 monoclonal antibody reacts with mouse PD-L2 (programmed death ligand 2) also known as B7-DC or CD273. PD-L2 is a 25 kDa type I transmembrane protein that belongs to the B7 family of the Ig superfamily. PD-L2 is expressed on monocytes, macrophages and subsets of dendritic cells. PD-L2 binds to its receptor, PD-1, found on CD4 and CD8 thymocytes as well as activated T and B lymphocytes and myeloid cells. Engagement of PD-L2 with PD-1 leads to inhibition of TCR-mediated T cell proliferation and cytokine production. The TY25 antibody has been reported to block PD-1 mediated interactions in vivo.

InVivoMAb anti-mouse PD-L2 (B7-DC) Specifications


Rat IgG2a, κ

Recommended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)

Mouse PD-L2 transfected cell line

Reported Applications
  • in vivo PD-L2 blockade
  • in vitro PD-L2 blockade
  • Immunohistochemistry (frozen)
  • Flow cytometry
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assy
  • >95%
  • Determined by SDS-PAGE
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives

0.2 μM filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.



References provided by Bioz:

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