InVivoMAb anti-mouse CD8 (Lyt 2.1)
Clone Catalog # Category
116-13.1 (HB129) BE0118 InVivoMab Antibodies
$350 - 3685

The 116-13.1 monoclonal antibody reacts with mouse CD8 also known as Lyt-2. The CD8 antigen is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). Like the TCR CD8 binds to class I MHC molecules displayed by antigen presenting cells (APC). CD8 is primarily expressed on the surface of cytotoxic T cells but can also be found on thymocytes natural killer cells and some dendritic cell subsets. CD8 most commonly exists as a heterodimer composed of one CD8╬▒and one CD8╬▓chain however it can also exist as a homodimer composed of two CD8╬▒chains. Both the CD8╬▒and CD8╬▓chains share significant homology to immunoglobulin variable light chains. The molecular weight of each CD8 chain is approximately 34 kDa. The 116-13.1 antibody exhibits depleting activity when used in vivo .


Mouse IgG2a

Recomended Isotype Control(s) InVivoMAb mouse IgG2a isotype control, unknown specificity
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer

CE mouse spleen cells and thymocytes

Reported Applications
  • in vivo CD8+ T cell depletion
  • Flow cytometry
  • <2EU/mg (<0.002EU/╬╝g)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAGE
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives

0.2 ╬╝M filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


Undiluted at 4┬░C in the dark