InVivoMAb anti-mouse TIM-1 (CD365)

Clone Catalog # Category
3D10 BE0314 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse TIM-1 (CD365)

The 3D10 monoclonal antibody reacts with mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. TIM-1 is a type I cell-surface glycoprotein and member of the Ig superfamily. TIM-1 is preferentially expressed on TH2 cells and has been identified as a stimulatory molecule for T cell activation. The TIM gene family, plays critical roles in regulating the immune response to viral infection. TIM-1 is also involved in allergic responses, asthma, and transplant tolerance. The 3D10 antibody has been shown to block TIM-1 in vivo and enhance atherosclerosis in mice studies.

InVivoMAb anti-mouse TIM-1 (CD365) Specifications

Isotype

Rat IgG1, κ

Recommended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol(BE0290)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Mouse TIM-1 (signal and IgV domains)/mouse IgG2a Fc fusion protein

Reported Applications
  • in vivo TIM-1 blockade
  • in vitro TIM-1 blockade
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark

RRID

AB_2754552