InVivoMAb anti-mouse TCR γ/δ

Clone Catalog # Category
UC7-13D5 BE0070 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse TCR γ/δ

The UC7-13D5 monoclonal antibody reacts with an epitope on the mouse γ/δ TCR (gamma delta T cell receptor) complex. The γ/δ TCR is expressed by a subset of T cells found in the thymus, peripheral lymphoid tissues, intestinal epithelium, epidermis, and peritoneum. The exact function, ligand, and specificity of γ/δ TCR-expressing T cells are not completely understood. Studies suggest that these cells recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play a role in regulating the immune response during bacterial infection. The UC7-13D5 antibody has been shown to activate γ/δ T cells in vitro and deplete γ/δ T cells when administered in vivo.

InVivoMAb anti-mouse TCR γ/δ Specifications

Isotype

Armenian Hamster IgG, κ

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Immunogen

Not available or unknown

Reported Applications
  • in vivo TCR γ/δ neutralization
  • in vitro γ/δ T cell stimulation
  • in vitro γ/δ T cell purification
  • Functional assays
  • Immunoprecipitation
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS + 0.01% Tween, pH 6.5
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein A

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_1107751