InVivoMab anti-mouse IL-3

Clone Catalog # Category
MP2-8F8 BE0282 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMab anti-mouse IL-3

The MP2-8F8 monoclonal antibody reacts with mouse IL-3, a pleiotropic cytokine produced primarily by activated T cells but also by activated mast cells, keratinocytes and neurons/astrocytes. IL-3 is highly species-specific, mature human and mouse IL-3 share only 29% sequence identity and human IL-3 does not show activity on mouse cells. IL-3 can stimulate the proliferation and differentiation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Additionally, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages. The MP2-8F8 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-3 as well as stimulate basophil proliferation when administered as a complex with IL-3.

InVivoMab anti-mouse IL-3 Specifications


Rat IgG1

Recommended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)

COS-expressed, recombinant mouse IL-3

Reported Applications
  • in vivo IL-3 neutralization
  • in vitro IL-3 neutralization
  • in vivo IL-3 receptor stimulation (as a complex with IL-3)
  • Flow cytometry
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAGE
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives

0.2 μM filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.



Molecular Weight

150 kDa

References provided by Bioz:

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