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InVivoMAb anti-mouse IL-2
Clone Catalog # Category
S4B6-1 BE0043-1 InVivoMab Antibodies
$95 - $3080

The S4B6-1 monoclonal antibody reacts with mouse IL-2, a 17 kDa cytokine that is mainly produced by T cells in response to antigenic or mitogenic stimulation. IL-2 is required for T cell proliferation and other activities crucial to the regulation of immunity. The cytokine can also stimulate the growth and differentiation of B cells, monocytes/macrophages, and NK cells. Additionally, IL-2 prevents autoimmune diseases by promoting the differentiation of certain immature T cells into regulatory T cells. The S4B6-1 antibody has been shown to neutralize IL-2 in vivo.

Isotype

Rat IgG2a

Recomended Isotype Control(s) InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 6.5 Dilution Buffer
Immunogen

Recombinant mouse IL-2

Reported Applications
  • in vivo IL-2 neutralization
  • in vivo IL-2 receptor stimulation (as a complex with IL-2)
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 6.5
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark

RRID

AB_1107705