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InVivoMAb anti-mouse IFNγ
Clone Catalog # Category
XMG1.2 BE0055 InVivoMab Antibodies
$95 - $3080

The XMG1.2 monoclonal antibody reacts with mouse IFNγ (interferon gamma) a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons. IFNγ is primarily produced by activated lymphocytes including T, B, NK cells, and ILCs. IFNγ exerts immunoregulatory, anti-proliferative, anti-viral, and proinflammatory activities and plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. Additionally, IFNγ induces the production of cytokines, Fc receptor, and adhesion molecules and up-regulates MHC class I and II antigen expression by antigen presenting cells during an immune response. IFNγ has also been shown to modulate macrophage effector functions, influence isotype switching and induce the secretion of immunoglobulins by B cells. IFNγ signals through the IFN gamma receptor which exists as a heterodimer composed of CD119 (IFN gamma receptor 1) and AF-1 (IFN gamma receptor 2). The IFNγ receptor is expressed ubiquitously on almost all cell types with the exception of mature erythrocytes. The XMG1.2 antibody is a neutralizing antibody.


Rat IgG1, κ

Recomended Isotype Control(s) InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
Recommended InVivoPure Dilution Buffer InVivoPure pH 8.0T Dilution Buffer

Recombinant mouse IFNγ

Reported Applications
  • in vivo IFNγ neutralization
  • in vitro IFNγ neutralization
  • Flow cytometry
  • Western blot
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAE
  • PBS + 0.01% Tween, pH 8.0
  • Contains no stabilizers or preservatives

0.2 μM filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


Undiluted at 4°C in the dark