InVivoMAb anti-mouse/rat MHC Class II (I-Ek/RT1-D)

Clone Catalog # Category
14-4-4S (HB32) BE0167 InVivoMab Antibodies
$95 - $3250
SDS Sheet

About InVivoMAb anti-mouse/rat MHC Class II (I-Ek/RT1-D)

The 14-4-4S monoclonal antibody reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. These MHC class II molecules are expressed primarily on the surface of B lymphocytes, macrophages, dendritic cells and other antigen presenting cells as well as a subset of T cells from H-2k bearing mice. These MHC molecules play a role in antigen presentation to T cells. The 14-4-4S antibody has been reported to block antigen presentation and induce differentiation of mouse cells expressing I-Ek.

InVivoMAb anti-mouse/rat MHC Class II (I-Ek/RT1-D) Specifications


Mouse IgG2a, κ

Recommended Isotype Control(s) InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)

C3H mouse skin graft and spleen cells

Reported Applications
  • in vivo blocking of antigen presentation
  • Flow cytometry
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
  • >95%
  • Determined by SDS-PAGE
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives

0.2 μM filtered


Purified from tissue culture supernatant in an animal free facility


Protein G


The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.



References provided by Bioz:

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