InVivoMAb anti-human CD71
The OKT-9 monoclonal antibody reacts with human CD71 also known as Transferrin receptor protein 1 (TfR1). CD71 is a 95 kDa type II transmembrane glycoprotein that is expressed by immature proliferating cells, reticulocytes, and erythroid precursors. CD71 influences cellular proliferation by mediating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. CD71 is a potential new target in cases of human leukemia and lymphoma.
|Recomended Isotype Control(s)||InVivoMAb mouse IgG1 isotype control, unknown specificity|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer|
Human acute lymphoblastic leukemia cells
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
Undiluted at 4°C in the dark