InVivoMAb anti-human N-cadherin (CD325)
The 8C11 monoclonal antibody reacts with human N-Cadherin, also known as CD325. N-Cadherin is a 130 kDa transmembrane protein and a member of the Cadherin superfamily. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts as well as in neural and muscle tissues. N-cadherin is involved in organ development during gastrulation and is required for establishment of left-right asymmetry. N-cadherin is also thought to provide a mechanism for transendothelial migration of cancer cells thus promoting metastasis.
|Recomended Isotype Control(s)||InVivoMAb mouse IgG1 isotype control, unknown specificity|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer|
Recombinant human N-cadherin extracellular domain
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
Undiluted at 4°C in the dark