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InVivoMAb anti-human N-cadherin (CD325)
Clone Catalog # Category
8C11 BE0184 InVivoMab Antibodies
$300 - 3080

The 8C11 monoclonal antibody reacts with human N-Cadherin, also known as CD325. N-Cadherin is a 130 kDa transmembrane protein and a member of the Cadherin superfamily. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts as well as in neural and muscle tissues. N-cadherin is involved in organ development during gastrulation and is required for establishment of left-right asymmetry. N-cadherin is also thought to provide a mechanism for transendothelial migration of cancer cells thus promoting metastasis.

Isotype

Mouse IgG1

Recomended Isotype Control(s) InVivoMAb mouse IgG1 isotype control, unknown specificity
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Recombinant human N-cadherin extracellular domain

Reported Applications
  • Western blot
  • Immunofluorescence
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark