InVivoMAb anti-HIV gp120
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About InVivoMAb anti-HIV gp120
The 55-36 monoclonal antibody reacts with human immunodeficiency virus (HIV) envelope glycoprotein 120 (gp120). gp120 is a 120 kDa glycoprotein exposed on the surface of the HIV envelope. gp120 is essential for virus entry into host cells as it plays a vital role in attachment to DC-SIGN cell surface receptors, sulfate proteoglycan, and CD4. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral particle with the host cell membrane.
InVivoMAb anti-HIV gp120 Specifications
|Recommended Isotype Control(s)||InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083)|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.