About InVivoMAb anti-HIV gp120
The 55-36 monoclonal antibody reacts with human immunodeficiency virus (HIV) envelope glycoprotein 120 (gp120). gp120 is a 120 kDa glycoprotein exposed on the surface of the HIV envelope. gp120 is essential for virus entry into host cells as it plays a vital role in attachment to DC-SIGN cell surface receptors, sulfate proteoglycan, and CD4. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral particle with the host cell membrane.
InVivoMAb anti-HIV gp120 Specifications
| Isotype | Mouse IgG1, κ |
| Recommended Isotype Control(s) | |
| Recommended Dilution Buffer | |
| Immunogen | Recombinant gp120 |
| Formulation |
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| Endotoxin |
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| Purity |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| RRID | AB_10950313 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |