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InVivoMAb anti-mouse Siglec-H

Clone Catalog # Category
440c BE0202 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse Siglec-H

The 440c monoclonal antibody recognizes mouse Siglec-H, a member of the CD33-related Siglec family. Siglec-H has been shown to be exclusively expressed on plasmacytoid dendritic cells (pDCs) and type I IFN-producing cells (IPC) in naïve mice. IPCs play a major role in the immune response to viruses. The 440c antibody has been shown to inhibit pDC function.

InVivoMAb anti-mouse Siglec-H Specifications

Isotype

Rat IgG2b

Recomended Isotype Control(s) InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Purified bone marrow-derived IPCs

Reported Applications
  • in vivo administration
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark

RRID

AB_10949014