InVivoMAb anti-mouse IL-1 R (CD121a)

Clone Catalog # Category
JAMA-147 BE0256 InVivoMab Antibodies
$95 - $3080
SDS Sheet

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About InVivoMAb anti-mouse IL-1 R (CD121a)

The JAMA-147 monoclonal antibody reacts with mouse IL-1 receptor (IL-1 R) type 1 also known as CD121a. IL-1 R is an 80 kDa transmembrane glycoprotein and a member of the immunoglobulin superfamily. The receptor is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. IL-1 R type 1 can bind both IL-1α and IL-1β. Upon ligand binding the type I receptor mediates all the known IL-1 biological responses.

InVivoMAb anti-mouse IL-1 R (CD121a) Specifications

Isotype

Armenian Hamster IgG, κ

Recomended Isotype Control(s) InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Immunogen

Extracellular domain of mouse IL-1 R type 1

Reported Applications

in vitro IL-1 R blockade

Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 6.0 0.01% Tween

  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

RRID

AB_2661843