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InVivoMAb anti-human/bovine LDLR
Clone Catalog # Category
C7 BE0133 InVivoMab Antibodies
$300 - 3080

The C7 monoclonal antibody reacts with human and bovine low-density lipoprotein receptor LDLR, a type I membrane protein. LDL is the major cholesterol-carrying lipoprotein in plasma. Cell surface LDLR controls the level of cholesterol in plasma by binding to and internalizing LDL and transporting it to lysosomes where the LDL is degraded. Mutations in LDLR are associated with familial hypercholesterolemia which is characterized by high levels of LDL in the blood.

Isotype

Mouse IgG2b

Recomended Isotype Control(s) InVivoMAb mouse IgG2b isotype control, unknown specificity
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Bovine adrenal LDL receptor

Reported Applications
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • Flow cytometry
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark