InVivoMAb anti-human IL-12 p70
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About InVivoMAb anti-human IL-12 p70
The 20C2 monoclonal antibody reacts with human interleukin-12 (IL-12), a heterodimeric 70 kDa (p70) cytokine consisting of two covalently linked subunits, 40 kDa (p40) and 35 kDa (p35). IL-12 is secreted by activated monocytes, macrophages, and dendritic cells in response to bacterial pathogens or products such as lipopolysaccharides (LPS). IL-12 is a potent regulator of cell-mediated immune responses and plays a key role in the development of Th1 responses, leading to IFNγ and IL-2 production.
InVivoMAb anti-human IL-12 p70 Specifications
Rat IgG1, κ
|Recommended Isotype Control(s)||
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol(BE0290)
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer(IP0070)|
Partially purified human IL-12 p70
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.