InVivoMAb anti-mouse F4/80
The CI:A3-1 monoclonal antibody reacts with mouse F4/80 also known as EMR1. F4/80 is a 160 kDa membrane glycoprotein belonging to the EGF-TM7 family. F4/80 is expressed on most tissue macrophages including peritoneal, lung, gut, thymus and splenic red pulp macrophages, as well as Kuffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells. F4/80's cognate ligand has not been identified however studies in mice have shown that F4/80 is important for cytokine production and induction regulatory T cells.
|Recomended Isotype Control(s)||InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin|
|Recommended InVivoPure Dilution Buffer||InVivoPure pH 7.0 Dilution Buffer|
C57BL/6 mouse thioglycollate stimulated peritoneal macrophages
0.2 μM filtered
Purified from tissue culture supernatant in an animal free facility
Undiluted at 4°C in the dark