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InVivoMAb anti-human/rat/fish AChR
Clone Catalog # Category
Mab35 (TIB-175) BE0123 InVivoMab Antibodies
$300 - 3080

The mAb35 (TIB-175) antibody reacts with human rat and fish acetylcholine receptor (AChR). The AChR is a heterodimeric receptor consisting of four subunits in a molar stoichiometry α2βγδ during the early embryonic stages or after denervation and α2βεδ in the adult form. The mAB35 antibody binds to the major immunogenic region of the α subunits. It has been shown to passively transfer experimental autoimmune myasthenia gravis.

Isotype

Rat IgG1

Recomended Isotype Control(s) InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
InVivoMAb rat IgG1 Isotype control, anti-trinitrophenol
Recommended InVivoPure Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen

Electrophorus electricus acetylcholine receptor

Reported Applications
  • EAMG induction in rats
  • Immunofluorescence
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

Undiluted at 4°C in the dark