InVivoMAb anti-human IL-9 (clone: MH9A4)

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The MH9A4 monoclonal antibody reacts with human IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. IL-9 promotes mast cell and T cell proliferation, stimulates mast cell accumulation in tissues, promotes ILC survival, enhances class-switching to IgE in B cells and alters haematopoietic progenitor cell activity. Additionally, IL-9 enhances mucus production from airway epithelial cells and alters barrier function in the intestines. IL-9 is thought to contribute to asthma. The MH9A4 antibody does not block the binding of IL-9 to the IL-9 receptor.

This Antibody Is Useful For:

  • Flow cytometry
  • ELISA

As always Bio X Cell antibodies are specifically formulated for in vivo use and feature:

  • 95% purity
  • Ultra-low endotoxin levels
  • Preservative, stabilizer, and carrier protein-free

Read how other researchers have used the anti-human IL-9 antibody.

 

Recommended Control and Buffer:

 

InVivoMAb mouse IgG2b isotype control, unknown specificity

InVivoMAb mouse IgG2b isotype control, unknown specificity

The MPC-11 monoclonal antibody is ideal for use as a non-reactive isotype-matched control for mouse IgG2b antibodies in most in vivo and in vitro applications.

 

 

 

InVivoPure pH 7.0 Dilution Buffer

InVivoPure™ dilution buffers are specifically formulated and tested to satisfy the stringent requirements for in vivo applications. They are extremely low in endotoxin, have been screened for murine pathogens, tested in animal models for toxicity and are formulated with respect to buffer composition and pH to satisfy the requirements of Bio X Cell’s antibodies.

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