Research

4 posts found

The program for central memory T cell generation is preserved intrinsically in CD8 T cells.

August 10, 2018

  Eun Young Choi’s group from the Seoul National University College of Medicine have discovered that CD4 T cell help is not required to… Read More

TIGIT blockade prevents NK cell exhaustion and elicits potent anti-tumor immunity

July 20, 2018

TIGIT deficiency in NK cells is sufficient to delay tumor growth in vivo and blockade of TIGIT via monoclonal antibodies reverses the exhaustion of anti-tumor NK cells in multiple tumor models and improves overall survival. Read More

Regulatory T cells use lymphotoxin beta receptor to migrate from tissues to lymph nodes

July 10, 2018

    Regulatory T cells use lymphotoxin beta receptor to migrate from tissues to lymph nodes Dr. Jonathan S. Bromberg’s group from the University… Read More

CD40 stimulation drives T cell immunity in cancer

July 1, 2018

    CD40 stimulation drives T cell immunity in cancer Drs. Katelyn Byrne and Robert Vonderheide from the University of Pennsylvania have discovered that… Read More